VistaraBio identifies vital link between protein trafficking mechanisms and PD-L1 biology in uterine endometrioid carcinomas (EC).

The creation of a Proximity PTM Map of PD-L1 by VistaraBio has paved the way for finding the first clues of protein traffic dysregulation and suggests rational steps in understanding the pathology of cancer cells!  In this context, abnormal protein trafficking has long been recognized as a critical aspect of endometrioid carcinoma, playing a role […]


Continue.. VistaraBio identifies vital link between protein trafficking mechanisms and PD-L1 biology in uterine endometrioid carcinomas (EC).

A proximity PTM map of PD-L1 identifies associations with mutations in Adenocarcinomas!

In the immuno-oncology therapeutics arena PD-L1 is a hotly investigated target both pre-clinically and in the clinic to harness the immune system to fight cancer. This protein has a highly complex biology, distributed in multiple cellular compartments although it’s presence on the cell surface of cancer cells and binding to the PD1 receptor on T […]


Continue.. A proximity PTM map of PD-L1 identifies associations with mutations in Adenocarcinomas!